| 產(chǎn)品編號 | bsm-63018R |
| 英文名稱 | Phospho-VASP (Ser156) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化血管擴張刺激磷蛋白重組兔單抗 |
| 別 名 | Vasodilator stimulated phosphoprotein; VASP. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:100-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 40 kDa |
| 檢測分子量 | 46 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human VASP around the phosphorylation site of S156: RRV-pS-NAG |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. SWISS: P50552 Gene ID: 7408 ????VASP屬于Ena-VASP蛋白家族，是一種肌動蛋白結(jié)合蛋白。細(xì)胞骨架動力學(xué)的調(diào)節(jié)在細(xì)胞粘附、細(xì)胞變形、細(xì)胞移動等生理過程中是必需的。VASP可能也參與細(xì)胞內(nèi)信號通道，該通道調(diào)節(jié)整聯(lián)蛋白與細(xì)胞外基質(zhì)間的相互作用。VASP被周期核苷酸依賴型激酶PKA與PKG所調(diào)節(jié),在一些腫瘤的分化、增值、轉(zhuǎn)移中起到一定的作用，在腫瘤中有較高的表達(dá)。 ????近年來的研究發(fā)現(xiàn)VASP在與細(xì)胞骨架調(diào)節(jié)有關(guān)的各種細(xì)胞行為中起著重要作用，如神經(jīng)細(xì)胞軸索的延伸、T細(xì)胞的移動、成纖維細(xì)胞的遷移等。 ????VAS |
