| 產(chǎn)品編號(hào) | bs-1772R |
| 英文名稱 | Cytokeratin 15 Rabbit pAb |
| 中文名稱 | 細(xì)胞角蛋白15抗體 |
| 別 名 | K1C15_HUMAN; Cytokeratin-15; CK 15; CK-15; CK15; Cytokeratin15; K15; K1CO; Keratin 15; Keratin 15 basic; Keratin 15 beta; Keratin complex 1 acidic gene 15; Keratin type I cytoskeletal 15; Keratin15; KRT 15; KRTB; KRTL15; keratin-15, basic; Type I cytoskeletal 15. |
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Specific References (2) | bs-1772R has been referenced in 2 publications.
[IF=5.116] Jian Liu. et al. Involvement of miRNA203 in the proliferation of epidermal stem cells during the process of DM chronic wound healing through Wnt signal pathways. Stem Cell Res Ther. 2020 Dec;11(1):1-10 IHC ; Rat.
[IF=2.24] Yang Rong-Hua, et al. An improved method for the isolation and culture of rat epidermal stem cells. International Journal of Clinical and?Experimental Pathology6.11 (2013): 2529-2534. ICC ; Rat.
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| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞外基質(zhì) |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CK15: 201-300/456 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region on chromosome 17q21.2. [provided by RefSeq]. Subunit: Heterotetramer of two type I and two type II keratins. Tissue Specificity: Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate. Similarity: Belongs to the intermediate filament family. SWISS: P19012 Gene ID: 3866 Database links: Entrez Gene: 3866 Human Entrez Gene: 16665 Mouse Omim: 148030 Human SwissProt: P19012 Human SwissProt: Q61414 Mouse Unigene: 654570 Human Unigene: 440010 Mouse Unigene: 153568 Rat 結(jié)構(gòu)蛋白（Structural Proteins） 細(xì)胞角蛋白15對(duì)角質(zhì)形成和細(xì)胞增殖活性起到一定的作用。 |
