產(chǎn)品編號 | bs-3637R |
英文名稱 | Rabbit Anti-Tetraspan 5 antibody |
中文名稱 | 四分子交聯(lián)體5抗體 |
別 名 | NET 4; TSPAN 5; NET4; Tetraspan 5; Tetraspan-5; Tetraspan NET 4; Tetraspan TM4SF; Tetraspanin 5; Tetraspanin5; Tetraspan5; Tspaw5; TM4SF9; Transmembrane 4 superfamily member 8; Transmembrane 4 superfamily member 9. |
研究領(lǐng)域 | 腫瘤 免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞粘附分子 細(xì)胞表面分子 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 29kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Tetraspan 5: 65-160/268 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Subcellular Location: Membrane; Multi-pass membrane protein (Probable). Similarity: Belongs to the tetraspanin (TM4SF) family. SWISS: P62079 Gene ID: 10098 Database links: Entrez Gene: 10098 Human Entrez Gene: 56224 Mouse Omim: 613136 Human SwissProt: P62079 Human SwissProt: P62080 Mouse Unigene: 118118 Human Unigene: 31927 Mouse Unigene: 98240 Rat 四分子交聯(lián)體5又稱四旋蛋白5,是四分子交聯(lián)體超家族是一組以四次跨膜及兩個(gè)大小不等的細(xì)胞外環(huán)狀結(jié)構(gòu)為主要特征的膜表面蛋白。Tspaw5超家族成員可以通過彼此間的相互聯(lián)系, 該家族的許多成員對惡性腫瘤的轉(zhuǎn)移有重要影響,它可與許多生長促進(jìn)分子和粘附分子結(jié)合,以往的研究主要集中在神經(jīng)系統(tǒng),它在神經(jīng)系統(tǒng)中高表達(dá),可以影響的神經(jīng)細(xì)胞及神經(jīng)膠質(zhì)細(xì)胞的粘附、運(yùn)動和增殖,對于神經(jīng)系統(tǒng)的形成和功能的維持起重要作用。 |