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VAPA Rabbit pAb (bs-4226R)  
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產(chǎn)品編號(hào) bs-4226R
英文名稱 VAPA Rabbit pAb
中文名稱 囊泡相關(guān)膜蛋白相關(guān)蛋白A抗體
別    名 VAMP A; VAMP associated protein A; VAP 33; VAP A; VAP33; Vesicle associated membrane protein associated protein A; VAPA_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VAPA: 101-200/249 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 VAPA is a type IV membrane protein, present in the plasma membrane, intracellular vesicles and may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Two transcript variants encoding distinct isoforms have been identified.

Function:
May play a role in vesicle trafficking.

Subunit:
Homodimer, and heterodimer with VAPB. Interacts with VAMP1, VAMP2, STX1A, BET1, SEC22C and with the C-terminal domain of OCLN. Interacts with OSBPL1A. Interacts (via MSP domain) with ZFYVE27; may retain ZFYVE27 in the endoplasmic reticulum and regulate its function in cell projections formation.

Subcellular Location:
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. Contains 1 MSP domain.

SWISS:
Q9P0L0

Gene ID:
9218

Database links:

Entrez Gene: 9218 Human

Entrez Gene: 30960 Mouse

Entrez Gene: 58857 Rat

Omim: 605703 Human

SwissProt: Q0VCY1 Cow

SwissProt: Q9P0L0 Human

SwissProt: Q9WV55 Mouse

SwissProt: Q9Z270 Rat

Unigene: 165195 Human

Unigene: 266767 Mouse

Unigene: 162275 Rat



產(chǎn)品圖片
Sample: NIH/3T3(Mouse) Cell Lysate at 30 ug Primary: Anti-VAPA (bs-4226R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD
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