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Fetuin A/AHSG Rabbit pAb (bs-2922R)  
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產(chǎn)品編號(hào) bs-2922R
英文名稱 Fetuin A/AHSG Rabbit pAb
中文名稱 胎球蛋白A
別    名 Fetuin-A; 59 kDa bone sialic acid containing protein; A2HS; Aa2 066; AHS; AHSG; alpha 2 HS glycoprotein; alpha 2 HS glycoprotein chain A; alpha 2 Z globulin; alpha 2HS glycoprotein; alpha2 Heremans Schmid glycoprotein; Asialofetuin; Ba alpha 2 glycoprotein; BSP; Countertrypin; FETUA; Fetuin A; Fetuin, mouse, homolog of; FetuinA; Glycoprotein PP63; HSGA; pp63; alpha-2-HS-glycoprotein chain A  
Specific References  (2)     |     bs-2922R has been referenced in 2 publications.
[IF=3.99] Naito, Chisato, et al. "Facilitatory effects of fetuin-A on atherosclerosis."Atherosclerosis (2016).  IHC-P ;  Rat.  
[IF=3.411] Yamanishi Kyosuke. et al. Exploring Molecular Mechanisms Involved in the Development of the Depression-Like Phenotype in Interleukin-18-Deficient Mice. Biomed Res Int. 2021;2021:9975865  WB ;  Mouse.  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 31/40 kDa
檢測分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Alpha-2-HS-glycoprotein chain A.: 201-300/367 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]

Function:
Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions.

Subunit:
Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond.

Subcellular Location:
Secreted.

Tissue Specificity:
Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins.

Similarity:
Belongs to the fetuin family.
Contains 2 cystatin fetuin-A-type domains.

SWISS:
Q9UGM5

Gene ID:
26998

Database links:

Entrez Gene: 197 Human

Entrez Gene: 26998 Human

Omim: 138680 Human

Omim: 605954 Human

SwissProt: P02765 Human

SwissProt: Q9UGM5 Human

Unigene: 324746 Human

Unigene: 81073 Human



產(chǎn)品圖片
Sample: liver (mouse)cell Lysate at 40 ug Primary: Anti- Fetuin A/AHSG (bs-2922R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 31kD Observed band size: 34 kD
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