日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
欧美日韩一区二区五,精品一区二区三区第35,夫妻性生活视频一区二区
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
KLK6 Rabbit pAb (bs-5870R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-5870R
英文名稱 KLK6 Rabbit pAb
中文名稱 激肽釋放酶6抗體
別    名 Bssp; hK 6; hK6; Kallikrein 6 precursor; Kallikrein related peptidase 6; Kallikrein-6; Kallikrein6; Kallikrein 6; Kallikrein-6; KLK 6; KLK6; KLK-6; Klk 7; Klk7; Klk-7; KLK 9; KLK9; KLK-9; Klk6; KLK6_HUMAN; Klk7; KLK9; mGK 1; mGK1; Neurosin; Protease M; Protease serine 18; Protease serine 9; PRSS 18; PRSS 9; PRSS18; PRSS9; Serine protease 18; Serine protease 9; SP 59; SP59; Tissue kallikrein; TK; Zyme; KLK6_HUMAN; Neurosin.  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  信號轉(zhuǎn)導  細胞粘附分子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 27 kDa
檢測分子量
細胞定位 細胞核 細胞漿 分泌型蛋白 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLK6: 217-244/244 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Function:
Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.

Subcellular Location:
Secreted. Nucleus, nucleolus. Cytoplasm. Mitochondrion. Microsome. Note=In brain, detected in the nucleus of glial cells and in the nucleus and cytoplasm of neurons. Detected in the mitochondrial and microsomal fractions of HEK-293 cells and released into the cytoplasm following cell stress.

Tissue Specificity:
In fluids, highest levels found in milk of lactating women followed by cerebrospinal fluid, nipple aspirate fluid and breast cyst fluid. Also found in serum, seminal plasma and some amniotic fluids and breast tumor cytosolic extracts. Not detected in urine. At the tissue level, highest concentrations found in glandular tissues such as salivary glands followed by lung, colon, fallopian tube, placenta, breast, pituitary and kidney. Not detected in skin, spleen, bone, thyroid, heart, ureter, liver, muscle, endometrium, testis, pancreas, seminal vesicle, ovary, adrenals and prostate. In brain, detected in gray matter neurons (at protein level). Colocalizes with pathological inclusions such as Lewy bodies and glial cytoplasmic inclusions. Overexpressed in primary breast tumors but not expressed in metastatic tumors.

Post-translational modifications:
Inactivated by autolytic cleavage after Arg-80.

Similarity:
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.

SWISS:
Q92876

Gene ID:
5653

Database links:

Entrez Gene: 5653 Human

Omim: 602652 Human

SwissProt: Q92876 Human

Unigene: 79361 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KLK6) Polyclonal Antibody, Unconjugated (bs-5870R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久pirn| 日本熟妇淫荡网| 91日韩国产自产| 女人骚货久久久| 亚洲免费AV观看不卡| 白白操白白操乱轮免费视频 | 国产二区 自拍| 国产性色一区二区| 男人喜欢操女人的小逼在线视频| 嗯嗯啊嗯哦嗯嗯啊视频| 亚洲欧洲综合一区二区三区四区| 国产精品扒开腿爽| 日B在线一二三| 人妖干人妖久久| 性色AV久久久久| 嗯啊好舒服网站| 久久最新视频中文字幕| 韩国熟妇XXXXX| 日本免费午夜视频| 大香蕉美乳在线| 国产二级三级精品| 日韩黑人AV| AV黄色成人网站| 激情丁香婷婷久久婷婷综合网| 亚洲乱码国产乱码精品精大量内射| 久久资源中文字幕| 日日嗷嗷色婷婷| 欧洲欧美日韩一级视频在线| 国产欧美亚洲大鸡吧| 日本无码一区二区无码三区有限公司 | 亚洲高清图片一区二区| 中文无码精品欧美| 少妇极品熟妇人妻无码| 最新天堂无码| 天天要天天干天天爽天天玩,| 日韩欧美中文字幕日韩欧美一级| 国产在线精品色欲sv| 经典国产一区二区| 欧美色图,亚洲色图校园春色| 欧美久久久无码资源免费| 天天日天天干天天天天射|