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Fast Myosin Skeletal Heavy chain Rabbit pAb (bs-5885R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號(hào) bs-5885R
英文名稱 Fast Myosin Skeletal Heavy chain Rabbit pAb
中文名稱 肌球蛋白重鏈抗體
別    名 heavy chain Myosin; adult 1; MGC133384; Myh 1; Myh1; MYH1_HUMAN; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle adult 1; Myosin light chain 1 alkali skeletal fast; Myosin-1; Myosin1; skeletal muscle; MYHa; MyHC-2x; MyHC-2X/D; MYHSA1; MYH1_HUMAN; MYL1; Myosin-1; Myosin heavy chain 1; Myosin heavy chain 2x; MyHC-2x; Myosin heavy chain IIx/d; MyHC-IIx/d; Myosin heavy chain, skeletal muscle, adult 1.  
Specific References  (5)     |     bs-5885R has been referenced in 5 publications.
[IF=7.014] Kong D et al. MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation. Cell Mol Life Sci. 2019 Jun 18.  ICF ;  Human.  
[IF=4.755] Zhang Lijiao. et al. Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a cigarette smoke–induced model of chronic obstructive pulmonary disease. FRONT PHYSIOL. 2022 Aug;0:1600  IHC, WB ;  Mouse.  
[IF=2.674] Tugeqin Bou. et al. Fast and slow myofiber-specific expression profiles are affected by noncoding RNAs in Mongolian horses. Comp Biochem Phys D. 2022 Mar;41:100942  IHC ;  Horses.  
[IF=2.573] Bao T et al. The distinct transcriptomes of fast-twitch and slow-twitch muscles in Mongolian horses. Comp Biochem Physiol Part D Genomics Proteomics. 2019 Dec 11;33:100649.  IHC-P ;  Horse.  
[IF=1.673] T. Gomi. et al. Comprehensive histological investigation of age-related changes in dermal extracellular matrix and muscle fibers in the upper lip vermilion.. Int J Cosmetic Sci. 2020 Aug;42(4):359-368  IF ;  Rat.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Chicken,Dog)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 223 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Myosin heavy chain 1: 901-1000/1939 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development. [provided by RefSeq, Jul 2008].

Function:
Muscle contraction.

Subunit:
Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).

Subcellular Location:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.

SWISS:
P12882

Gene ID:
4619

Database links:

Entrez Gene: 281337 Cow

Entrez Gene: 4619 Human

Entrez Gene: 17879 Mouse

Entrez Gene: 287408 Rat

Omim: 160730 Human

Omim: 160740 Human

SwissProt: Q9BE40 Cow

SwissProt: P12882 Human

SwissProt: Q5SX40 Mouse

SwissProt: Q9TV61 Pig

Unigene: 689619 Human

Unigene: 477065 Mouse



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