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REG1A Rabbit pAb (bs-6183R)  
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產(chǎn)品編號(hào) bs-6183R
英文名稱 REG1A Rabbit pAb
中文名稱 胰島細(xì)胞再生因子ICRF抗體
別    名 ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 beta; Lithostathine-1-alpha; P19; Pancreatic stone protein 2; Pancreatic stone protein; Pancreatic thread protein; PSP; PSPS; PSPS1; PSPS2; PTP; REG 1 beta; REG; REG-1-alpha; REG1A; REG1A_HUMAN; REG1B; Regenerating islet derived protein 1 beta; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; REGL.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 16 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human REG1A/REG1 alpha: 101-166/166 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Reg protein is stimulated during the regeneration of pancreatic islets. In human, there are four REG family genes; REG 1 alpha, REG 1 beta, REG-related sequence (RS) and HIP/PAP. These Reg-related proteins are classified into four subfamilies according to their amino-acid sequences, but they share a similar structure and physiological function.

Function:
Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration.

Subcellular Location:
Secreted.

Tissue Specificity:
In pancreatic acinar cells and, in lower levels, in brain. Enhanced expression of PSP-related transcripts and intraneuronal accumulation of PSP-like proteins is found in brain from Alzheimer disease and Down syndrome patients.

Post-translational modifications:
The composition of the O-linked carbohydrate on Thr-27 is complex and varied. In the crystallographic structure, the attached sugar appears to be N-acetylglucosamine, typical of an intracellular protein, rather than N-acetylgalactosamine.

Similarity:
Contains 1 C-type lectin domain.

SWISS:
P05451

Gene ID:
5967

Database links:

Entrez Gene: 5967 Human

Omim: 167770 Human

SwissProt: P05451 Human

Unigene: 4158 Human

Unigene: 49407 Human

Unigene: 708865 Human



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