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TEM7R Rabbit pAb (bs-6300R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-6300R
英文名稱 TEM7R Rabbit pAb
中文名稱 腫瘤血管內(nèi)皮標(biāo)記相關(guān)蛋白質(zhì)7抗體
別    名 Tumor endothelial marker 7 related protein; Plexin domain containing 2; Plexin domain containing protein 2; Plexin domain-containing protein 2; PLXDC 2; plxdc2; PXDC2_HUMAN; TEM7R; Tumor endothelial marker 7-related protein.  
研究領(lǐng)域 腫瘤  血管內(nèi)皮細(xì)胞  腫瘤細(xì)胞生物標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TEM7R.: 101-200/529 <Extracellular>
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 TEM7R also known as PLXDC2 is a 529 amino acid single-pass type I membrane protein containing one PSI domain and belonging to the plexin family. Localizing to membrane, TEM7R is expressed in endothelial cells of the stroma, as well as in limbs, lung buds, developing heart, spinal cord and dorsal root ganglia. TEM7R interacts with cortactin and may play a role in tumor angiogenesis. Existing as three alternatively spliced isoforms, the gene encoding TEM7R maps to human chromosome 10p12.31. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Function:
May play a role in tumor angiogenesis.

Subunit:
Interacts with CTTN.

Subcellular Location:
Membrane; Single-pass type I membrane protein

Tissue Specificity:
Expressed in the endothelial cells of the stroma but not in the endothelial cells of normal colonic tissue.

Similarity:
Belongs to the plexin family.
Contains 1 PSI domain.

SWISS:
Q6UX71

Gene ID:
84898

Database links:

Entrez Gene: 84898 Human

Entrez Gene: 67448 Mouse

Entrez Gene: 361282 Rat

Omim: 606827 Human

SwissProt: Q6UX71 Human

SwissProt: Q9DC11 Mouse

Unigene: 658134 Human

Unigene: 313938 Mouse

Unigene: 394655 Mouse



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