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Rabbit Anti-Granzyme K  antibody (bs-6788R)  
~~~促銷代碼KT202411~~~
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產品編號 bs-6788R
英文名稱 Rabbit Anti-Granzyme K  antibody
中文名稱 顆粒酶K抗體
別    名 Fragmentin 3; Fragmentin-3; Fragmentin3; GRAK_HUMAN; Granzyme 3; Granzyme K; Granzyme K precursor; Granzyme-3; Granzyme3; GranzymeK; GZMK; NK TRYP 2; NK TRYP2; NK tryptase 2; NK-TRYP-2; NK-tryptase-2; NKTRYP2; Serine protease granzyme 3; TRYP 2; TRYP2; Tryptase II; TryptaseII.  
研究領域 細胞生物  免疫學  信號轉導  細胞凋亡  轉錄調節(jié)因子  細胞外基質  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Horse)
產品應用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 26kDa
細胞定位 細胞漿 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Granzyme K: 51-250/264 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008].

Subcellular Location:
Secreted. Cytoplasmic granule.

Tissue Specificity:
Expressed in lung, spleen, thymus and peripheral blood leukocytes.

Similarity:
Belongs to the peptidase S1 family. Granzyme subfamily.
Contains 1 peptidase S1 domain.

SWISS:
P49863

Gene ID:
3003

Database links:

Entrez Gene: 3003 Human

Entrez Gene: 14945 Mouse

Entrez Gene: 29165 Rat

Omim: 600784 Human

SwissProt: P49863 Human

SwissProt: O35205 Mouse

SwissProt: P49864 Rat

Unigene: 277937 Human

Unigene: 56993 Mouse

Unigene: 11190 Rat



產品圖片
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-Granzyme K (bs-6788R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 26 kD Observed band size: 26 kD
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