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ccnb1ip1 Rabbit pAb (bs-7784R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-7784R
英文名稱 ccnb1ip1 Rabbit pAb
中文名稱 周期蛋白B1結(jié)合蛋白1抗體
別    名 C14orf18; CCNB1IP1; Chromosome 14 open reading frame 18; CIP1_HUMAN; Cyclin B1 interacting protein 1; Cyclin-B1-interacting protein 1; E3 ubiquitin-protein ligase CCNB1IP1; Enhancer of invasion 10; HEI10; Human enhancer of invasion 10.  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  細(xì)胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 32 kDa
檢測分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ccnb1ip1: 151-250/277 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.
Tissue specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.

Function:
E3 ubiquitin-protein ligase. Modulates cyclin B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis.

Subunit:
Binds CCNB1 and UBE2L3.

Subcellular Location:
Nucleus. Chromosome. Note=May associate with segregating chromosomes during metaphase and anaphase.

Tissue Specificity:
Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung.

Post-translational modifications:
Ubiquitinated; autoubiquitinated.
Phosphorylated by CDK1 on serine or threonine residues (in vitro).

Similarity:
Contains 1 RING-type zinc finger.

SWISS:
Q9NPC3

Gene ID:
57820

Database links:

Entrez Gene: 57820 Human

Omim: 608249 Human

SwissProt: Q9NPC3 Human

Unigene: 107003 Human



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