日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲熟女乱综合一区二区,av不卡手机在线观看
首頁(yè) > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
Factor X heavy chain Rabbit pAb (bs-7762R)  
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7762R
英文名稱 Factor X heavy chain Rabbit pAb
中文名稱 凝血因子10抗體
別    名 Activated factor Xa heavy chain; Coagulation factor; Coagulation factor X; EC 3.4.21.6; F10 antibody FA10_HUMAN; Factor Xa; FX; FXA; Prothrombinase; Stuart factor; Stuart Prower factor; Stuart-Prower factor.  
Specific References  (4)     |     bs-7762R has been referenced in 4 publications.
[IF=3.277] Gera,et al.Local Regulation of Thrombin Activity by Factor Xa in Peripheral Nerve Schwann Cells.(2018) Neuroscience. 371:445-454.  IF(IHC-F) + IF(ICC) + WB ;  Mouse + Human.  
[IF=3.161] Shavit Stein E et al. Thrombin Inhibition Reduces the Expression of Brain Inflammation Markers upon Systemic LPS Treatment.Neural Plast. 2018 Jun 19;2018:7692182.  WB ;  Mouse.  
[IF=2.81] Shimon et al. Recovery from trauma induced amnesia correlates with normalization of thrombin activity in the mouse hippocampus. (2017) PLoS.One. 12:e0188524  WB ;  Mouse.  
[IF=] Tumlin,et al.Methods and Drug Therapies for Patency of Occluded Blood Vessels Following Angioplasty.(2017) . :.  IHC ;  Human.  
研究領(lǐng)域 心血管  細(xì)胞生物  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Rat,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測(cè)分子量
細(xì)胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human factor Xa heavy chain: 351-448/488 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]

Function:
Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.

Subunit:
The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds. Forms heterodimer with SERPINA5.

Subcellular Location:
Secreted.

Tissue Specificity:
Plasma; synthesized in the liver.

Post-translational modifications:
The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans.
The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.

DISEASE:
Defects in F10 are the cause of factor X deficiency (FA10D) [MIM:227600]. A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis.

Similarity:
Belongs to the peptidase S1 family.
Contains 2 EGF-like domains.
Contains 1 Gla (gamma-carboxy-glutamate) domain.
Contains 1 peptidase S1 domain.

SWISS:
P00742

Gene ID:
2159

Database links:

Entrez Gene: 2159 Human

Omim: 227600 Human

SwissProt: P00742 Human

Unigene: 361463 Human

 



版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
久久久久久久久久久青青| 久久久精品韩国电影| 青青青久久久| 日本中文字幕在线更新| 久久综合福利视频| 淫国产精品| 精品欧美另类国产| 亚洲国产一区高潮| 啪啪啪免费看不卡| 久久国产精品久久精品国产6| 午夜日骚逼视频| 日韩欧美裸体精品一区二区| 亚洲一区二区三区在线日韩 | 草草影院在线无毒不卡| 欧美日人妻一区二区三区| 91偷拍一区二区| 谷城县| 天天射天天日天天射天天日春药高潮| 日韩偷怕自拍| 国产精品伦理九九| 凌辱人妻精品久久| 日本人妻视频一区| 欧美日韩中字无码| 国产精品自拍porn| 天天色婷婷色| 麻豆一区二区三区国产| 人人色91| 丰满人妻视频| 青操视频在线观看| 亚洲一二三区性色| 99久久综合精品国产首员无码 | 一区二区三区女厕偷拍| 欧美nZ日韩nZ国产nZ成人在线| 美女在线免费成人| 综合国产18| av噜在线| 日本国产欧美区| 欧美色一区二区国产乱 | 中文一区二区二区免费毛片| av在线播不卡| 欧美黄片,欧美黄片|