日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
人妻人人基地,蜜臀AV网扯,夫妻伦理av在线
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
APLP1 Rabbit pAb (bs-8465R)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-8465R
英文名稱 APLP1 Rabbit pAb
中文名稱 淀粉樣蛋白β前體樣蛋白1抗體
別    名 AMYLOID BETA A4 PRECURSOR-LIKE PROTEIN 1; AMYLOID PRECURSOR-LIKE PROTEIN; Amyloid-like protein 1 precursor; APLP 1; APLP; APLP-1; Aplp1; APLP1_HUMAN; C30.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  Alzheimer's  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse (predicted: Human,Rat,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 68 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human APLP1: 1-100/650 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.

Function:
May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.
The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).

Subunit:
Monomer and homodimer. Heparin binding promotes homodimerization. Binds, via its C-terminus, to the PID domain of several cytoplasmic proteins, including APBB and APBA family members, MAPK8IP1 and Dab1 (By similarity). Binding to Dab1 inhibits its serine phosphorylation (By similarity). Interacts with CPEB1. Interacts (via NPXY motif) with DAB2 (via PID domain); the interaction is impaired by tyrosine phosphorylation of the NPXY motif. Interacts (via NPXY motif) with DAB1 (By similarity).

Subcellular Location:
Cell membrane and Cytoplasm. C-terminally processed in the Golgi complex.

Tissue Specificity:
Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD).

Post-translational modifications:
Proteolytically cleaved by caspases during neuronal apoptosis. Cleaved, in vitro, at Asp-620 by caspase-3 (By similarity).
N- and O-glycosylated. O-glycosylation with core 1 or possibly core 8 glycans. Glycosylation on Ser-227 is the preferred site to Thr-228.

Similarity:
Belongs to the APP family.

SWISS:
P51693

Gene ID:
333

Database links:

Entrez Gene: 333 Human

Entrez Gene: 11803 Mouse

Entrez Gene: 502317 Rat

Omim: 104775 Human

SwissProt: P51693 Human

SwissProt: Q03157 Mouse

Unigene: 74565 Human

Unigene: 2381 Mouse



產(chǎn)品圖片
Sample: Brain (Mouse) Lysate at 40 ug Primary: Anti-APLP1 (bs-8465R )at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 68 kD Observed band size: 68 kD
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
va在线mf| 中文播放一区二区三区| 91婷婷韩国欧美一区二区| Av黄色的在线看| 性感91美女黄色小网站| 免费视频抽插视频| 日本天天爽天天天天做| 99国产小视频2019| 一二三日韩无码| 欧美 日韩 亚洲 一区二区| 欧美-91Av看片网| 色呦呦人人视屏| 欧洲99影视一区二区三区| 国产无吗一区二区三区在线 | 99re 国产| 韩日中文字幕成人网| 国产图片一二三区在线| 色区一二三| 亚洲高清AV无码电影| 日韩产品久久久| 国产乱伦精品一区二区三区免费| 999久久久网站| 黄色的免费网站| 黑人大吊午夜一区| 日本一区二区三区视屏在线| 黄片一级片欧美一区二区| 日本一区精品久久| 欧美三级久久久久久| 国产日韩欧美精选合集| 国产欧美大片一区二区三区| 精品一区二区三区天| 成人激情五月天婷婷网| 国内精品久久久久国产妓女偷| 俄罗斯大鸡巴插女人| 日韩欧一级| 石门县| 欧美日韩成人变态| 操比大鸡巴| 青娱乐极品视觉一区二区三区| 天天日天天爽天天干天天摸| 美女站着操逼|