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KCNE4 Rabbit pAb (bs-12172R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-12172R
英文名稱 KCNE4 Rabbit pAb
中文名稱 鉀離子通道蛋白家族成員4抗體
別    名 Minimum potassium ion channel related peptide 3; MinK related peptide 3; Potassium channel subunit beta MiRP3; Potassium voltage gated channel subfamily E member 4; KCNE4_HUMAN.  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 18 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNE4 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the embryo and in adult uterus. [provided by RefSeq, Jul 2008].

Function:
Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. May associate with KCNQ1/KVLTQ1 and inhibit potassium current.

Subunit:
Associates with KCNQ1/KVLQT1 (Probable).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.

Similarity:
Belongs to the potassium channel KCNE family.

SWISS:
Q8WWG9

Gene ID:
23704

Database links:

Entrez Gene: 23704 Human

SwissProt: Q8WWG9 Human



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