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TCP1 alpha Rabbit pAb (bs-12292R)  
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產(chǎn)品編號(hào) bs-12292R
英文名稱 TCP1 alpha Rabbit pAb
中文名稱 分子伴侶復(fù)合體TCP-1α抗體
別    名 AI528772; c-cpn; CCT alpha; CCT; CCT-alpha; CCT1; Ccta; CCTalpha; D6S230E; MGC133746; p63; T complex 1; T complex locus TCP 1; T complex protein 1 alpha subunit; T complex protein 1; T-complex homolog TCP1; T-complex protein 1 subunit alpha; T-complex protein 1 subunit alpha B; Tailless complex polypeptide 1; Tailless complex polypeptide 1A; Tailless complex polypeptide 1B; TCP 1 alpha; Tcp-1; TCP-1-alpha; TCP1; TCPA_HUMAN; Tp63; TRic.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human TCP1 alpha: 225-340/556 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Function:
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Subunit:
Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG. Component of the BBS/CCT complex composed at least of MKKS, BBS10, BBS12, TCP1, CCT2, CCT3, CCT4, CCT5 AND CCT8.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton, centrosome.

Similarity:
Belongs to the TCP-1 chaperonin family.

SWISS:
P17987

Gene ID:
6950

Database links:

Entrez Gene: 512043 Cow

Entrez Gene: 42649 Drosophila melanogaster

Entrez Gene: 6950 Human

Entrez Gene: 21454 Mouse

Entrez Gene: 100153485 Pig

Entrez Gene: 100302435 Rabbit

Entrez Gene: 24818 Rat

Entrez Gene: 851798 Saccharomyces cerevisiae

Omim: 186980 Human

SwissProt: Q32L40 Cow

SwissProt: P12613 Drosophila melanogaster

SwissProt: P17987 Human

SwissProt: P11983 Mouse

SwissProt: P28480 Rat

SwissProt: P12612 Saccharomyces cerevisiae



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti- TCP1 alpha (bs-12292R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD
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