| 產(chǎn)品編號 | bs-12363R |
| 英文名稱 | Rabbit Anti-FLRT3 antibody |
| 中文名稱 | 富含亮氨酸跨膜纖連蛋白3抗體 |
| 別 名 | FLRT3_HUMAN; Leucine-rich repeat transmembrane protein FLRT3; KIAA1469; Fibronectin-like domain-containing leucine-rich transmembrane protein 3; UNQ856/PRO1865; |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 信號轉(zhuǎn)導(dǎo) 干細(xì)胞 細(xì)胞分化 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 70 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FLRT3 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
FLRT3 is a 649 amino acid single-pass type I membrane protein that contains one fibronectin type-III domain and ten leucine-rich repeats and belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. Expressed in heart, liver, lung, kidney, pancreas, brain, placenta and skeletal muscle, FLRT3 is thought to be involved in receptor signaling events and may play a role in both cell adhesion neurite outgrowth. Defects in the gene encoding mouse FLRT3 may lead to ventral closure, headfold fusion and endoderm migration defects, suggesting that FLRT3 is important for proper cell differentiation and development. FLRT3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 20. Function: May have a function in cell adhesion and/or receptor signaling. Subcellular Location: Membrane; Single-pass type I membrane protein (Probable). Tissue Specificity: Expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. Similarity: Contains 1 fibronectin type-III domain. Contains 10 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. SWISS: Q9NZU0 Gene ID: 23767 Database links: Entrez Gene: 428552 Chicken Entrez Gene: 23767 Human Entrez Gene: 71436 Mouse SwissProt: F1NUK7 Chicken SwissProt: Q9NZU0 Human |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Rat Cerebrum tissue lysates
Lane 2: Rat Lung tissue lysates
Primary: Anti-FLRT3 (bs-12363R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70 kDa
Observed band size: 73 kDa
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