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GJA10 Rabbit pAb (bs-13362R)  
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50ul/1180.00元
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產(chǎn)品編號(hào) bs-13362R
英文名稱 GJA10 Rabbit pAb
中文名稱 間隙連接蛋白10抗體
別    名 Gap junction alpha 10; Connexin-62; Cx62; CXA10_HUMAN; Gap junction alpha 10; Gap junction alpha 10 protein; Gap junction alpha-10 protein; Gap junction protein alpha 10 59kDa; GJA10; MGC50985; RP11-63K6.6; Gap junction alpha 10; Connexin 58; Connexin 59; Connexin-62; CX58; CX59; Cx62; CXA10_HUMAN; Gap junction alpha 10; Gap junction alpha 10 protein; Gap junction alpha 9 protein; Gap junction alpha-10 protein; Gap junction protein alpha 10 59kDa; Gap junction protein alpha 9 59kDa; GJA10; MGC50985.  
研究領(lǐng)域 心血管  細(xì)胞生物  細(xì)胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Chicken)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 62 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GJA10: 151-250/543 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].

Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane. Cell junction; gap junction.

Tissue Specificity:
Expressed in skeletal muscle and heart.

Similarity:
Belongs to the connexin family. Alpha-type (group II) subfamily.

Database links:

UniProtKB/Swiss-Prot: Q969M2.1

Entrez Gene: 84694 Human

Omim: 611924 Human

SwissProt: P57773 Human

SwissProt: Q969M2 Human

Unigene: 334499 Human

Unigene: 632402 Human

 



產(chǎn)品圖片
Tissue/cell: Rat skeletal muscle; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-GJA10 Polyclonal Antibody, Unconjugated(bs-13362R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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