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LETM1 Rabbit pAb (bs-15591R)  
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產品編號 bs-15591R
英文名稱 LETM1 Rabbit pAb
中文名稱 LETM1蛋白抗體
別    名 LETM 1; LETM1 and EF hand domain containing protein 1, mitochondrial; LETM1 and EF-hand domain-containing protein 1; Letm1; LETM1_HUMAN; Leucine zipper EF hand containing transmembrane protein 1; Leucine zipper-EF-hand-containing transmembrane protein 1; Mdm38 homolog; mitochondrial; ZNF300 bs-0628R  
研究領域 細胞生物  免疫學  信號轉導  細胞類型標志物  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Chicken,Dog,Horse)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 71 kDa
檢測分子量
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LETM1: 101-200/739 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009].

Function:
Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.

Subunit:
Can form 2 complexes: a major (300 kDa) and a minor complex (500-600 kDa). Interacts with BCS1L.

Subcellular Location:
Mitochondrion inner membrane; Single-pass membrane protein.

Similarity:
Contains 1 EF-hand domain. Contains 1 LETM1 domain.

SWISS:
O95202

Gene ID:
3954

Database links:

Entrez Gene: 3954 Human

Omim: 604407 Human

SwissProt: O95202 Human

Unigene: 120165 Human



產品圖片
Sample: K562(Human) Cell Lysate at 30 ug MOLT-4(Human) Cell Lysate at 30 ug A549(Human) Cell Lysate at 30 ug HL60(Human) Cell Lysate at 30 ug Primary: Anti- LETM1 (bs-15591R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 71 kD Observed band size: 75 kD
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