產(chǎn)品編號 | bs-16008R |
英文名稱 | FAM5C Rabbit pAb |
中文名稱 | FAM5C蛋白抗體 |
別 名 | B830045N13Rik; BMP/retinoic acid inducible neural specific protein 3; BRINP3; BRNP3_HUMAN; DBCCR1 like protein 1; DBCCR1L; DBCCR1L1; Family with sequence similarity 5, member C; MGC107461; MGC40674; OTTMUSP00000028549; Protein FAM5C; RP11-445K1.1; RP23-212I24.1. |
研究領(lǐng)域 | 細胞生物 交換蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Pig,Sheep,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 85 kDa |
檢測分子量 | |
細胞定位 | 細胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FAM5C: 681-766/766 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
FAM5C belongs to the FAM5 family. Function: Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development. Subcellular Location: Secreted Tissue Specificity: Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues. Similarity: Belongs to the BRINP family. Contains 1 MACPF domain. SWISS: Q76B58 Gene ID: 339479 Database links: Entrez Gene: 339479 Human SwissProt: Q76B58 Human |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Rat stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; An
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