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Rabbit Anti-FCRL1  antibody (bs-16064R)  
~~~促銷代碼KT202411~~~
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16064R
英文名稱 Rabbit Anti-FCRL1  antibody
中文名稱 CD307a抗體
別    名 CD307a; Fc receptor homolog 1; Fc receptor like protein 1; Fc receptor-like protein 1; FcR like protein 1; FcR-like protein 1; FCRH 1; FcRH1; FCRL 1; FcRL1; FCRL1_HUMAN; hIFGP 1; hIFGP1; IFGP 1; IFGP family protein 1; IFGP1; Immune receptor translocation associated protein 5; Immune receptor translocation-associated protein 5; immunoglobulin superfamily Fc receptor, gp42; IRTA 5; IRTA5; RP11 367J7.7.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FCRL1: 251-350/429 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Function:
May function as an activating coreceptor in B-cells. May function in B-cells activation and differentiation.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Primarily expressed in secondary lymphoid tissues by mature subsets of B-cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B-cells (at protein level).

Post-translational modifications:
Phosphorylated on tyrosines upon activation.

Similarity:
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.

SWISS:
Q96LA6

Gene ID:
115350

Database links:

Entrez Gene: 115350 Human

Omim: 606508 Human

SwissProt: Q96LA6 Human

Unigene: 656112 Human



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