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FRRS1 Rabbit pAb (bs-16181R)  
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50ul/1180.00元
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產(chǎn)品編號(hào) bs-16181R
英文名稱 FRRS1 Rabbit pAb
中文名稱 FRRS1蛋白抗體
別    名 Ferric-chelate reductase 1; frrs1; FRRS1_HUMAN; SDFR2; SDR-2; SDR2; Stromal cell derived factor receptor 2 homolog; Stromal cell-derived receptor 2.  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Sheep,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 66 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRRS1: 301-400/592 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]

Function:
Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm.

Subcellular Location:
Membrane.

Similarity:
Belongs to the FRRS1 family. Contains 1 cytochrome b561 domain. Contains 1 DOMON domain. Contains 1 reelin domain.

SWISS:
Q6ZNA5

Gene ID:
391059

Database links:

Entrez Gene: 391059 Human

Omim: 611578 Human

SwissProt: Q6ZNA5 Human

Unigene: 454779 Human

 



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FRRS1) Polyclonal Antibody, Unconjugated (bs-16181R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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