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TIMM23 Rabbit pAb (bs-7375R)  
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產(chǎn)品編號 bs-7375R
英文名稱 TIMM23 Rabbit pAb
中文名稱 線粒體前體蛋白TIMM23抗體
別    名 MGC22767; MGC93478; Mitochondrial import inner membrane translocase subunit Tim23; Predicted protein of HQ1197; PRO1197; TIM23; TIM23_HUMAN; TIM-23; TIMM 23; TIMM23; Translocase of inner mitochondrial membrane 23(yeast) homolog; Translocase of inner mitochondrial membrane 23 homolog(yeast); Translocase of inner mitochondrial membrane 23 homolog B; Translocation of mitochondrial precursor proteins.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TIMM23: 111-209/209 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 TIMM23 nomenclature and NM_006327.2 were associated with GeneID:10431 in build 37.1. Because of assembly problems in this region, it was later determined that GeneID:100287932 correctly represents the location of TIMM23. TIMM23 is now associated with GeneID:100287932 and NM_006327.2. [17 Mar 2010]

Function:
TIMM23 belongs to the Tim17/Tim22/Tim23 family and is an essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

Subunit:
Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50; within this complex, directly interacts with TIMM50. The complex interacts with the TIMM44 component of the PAM complex and with DNAJC15.

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein.

Similarity:
Belongs to the Tim17/Tim22/Tim23 family.

SWISS:
O14925

Gene ID:
10431

Database links:

Entrez Gene: 10431 Human

Omim: 605034 Human

SwissProt: O14925 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TIMM23) Polyclonal Antibody, Unconjugated (bs-7375R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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