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TOMM40 Rabbit pAb (bs-17227R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-17227R
英文名稱 TOMM40 Rabbit pAb
中文名稱 TOMM40抗體
別    名 TOM40_HUMAN; Mitochondrial import receptor subunit TOM40 homolog; C19orf1; PEREC1; TOM40; PEREC1; PER-EC1; D19S1177E; Protein Haymaker; Translocase of outer membrane 40 kDa subunit homolog; p38.5;  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Rat (predicted: Human,Mouse,Pig,Sheep,Cow,Dog,Horse,Xenopus laevis)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 37 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TOMM40: 101-200/361 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is localized in the outer membrane of the mitochondria. It is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for import of protein precursors into mitochondria. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015]

Function:
Channel-forming protein essential for import of protein precursors into mitochondria.

Subunit:
Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 7 different proteins (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70). Interacts with mitochondrial targeting sequences.

Subcellular Location:
Mitochondrion outer membrane.

Similarity:
Belongs to the Tom40 family.

SWISS:
O96008

Gene ID:
10452

Database links:

Entrez Gene: 10452 Human

Entrez Gene: 510219 Cow

Entrez Gene: 611055 Dog

Entrez Gene: 53333 Mouse

Entrez Gene: 308416 Rat

Entrez Gene: 380301 Xenopus laevis

SwissProt: Q1LZB5 Cow

SwissProt: O96008 Human

SwissProt: Q9QYA2 Mouse

SwissProt: Q75Q40 Rat

SwissProt: Q7ZTM6 Xenopus laevis



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TOMM40) Polyclonal Antibody, Unconjugated (bs-17227R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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