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NDUFB1 Rabbit pAb (bs-19079R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價

產(chǎn)品編號 bs-19079R
英文名稱 NDUFB1 Rabbit pAb
中文名稱 NDUFB1蛋白抗體
別    名 CI-MNLL; Complex I-MNLL; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; NADH-ubiquinone oxidoreductase MNLL subunit; NDUB1_HUMAN; NDUFB1.  
研究領域 腫瘤  細胞生物  信號轉(zhuǎn)導  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 7 kDa
檢測分子量
細胞定位 細胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NDUFB1: 21-58/58 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 NDUFB1 is a 58 amino acid single-pass membrane protein that localizes to the matrix side of the mitochondrial membrane. A member of the complex I NDUFB1 subunit family, NDUFB1 is encoded by a gene that maps to human chromosome 14q32.12. Chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subcellular Location:
Mitochondrion inner membrane.

Similarity:
Belongs to the complex I NDUFB1 subunit family.

SWISS:
O75438

Gene ID:
4707

Database links:

Entrez Gene: 4707 Human

SwissProt: O75438 Human

Unigene: 183435 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NDUFB1) Polyclonal Antibody, Unconjugated (bs-19079R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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