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ZHX1 Rabbit pAb (bs-19163R)  
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產品編號 bs-19163R
英文名稱 ZHX1 Rabbit pAb
中文名稱 鋅指及同源結構域蛋白1抗體
別    名 ZHX 1; ZHX1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; Zinc fingers and homeoboxes 1; Zinc fingers and homeoboxes protein 1.  
研究領域 細胞生物  免疫學  轉錄調節(jié)因子  鋅指蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Sheep,Cow,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZHX1: 551-650/873 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene. [provided by RefSeq, Feb 2011]

Function:
Acts as a transcriptional repressor.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the ZHX family.
Contains 2 C2H2-type zinc fingers.
Contains 5 homeobox DNA-binding domains.

SWISS:
Q9UKY1

Gene ID:
11244

Database links:

Entrez Gene: 11244 Human

Entrez Gene: 420347 Chicken

Entrez Gene: 22770 Mouse

Entrez Gene: 171159 Rat

Omim: 604764 Human

SwissProt: Q9UKY1 Human

SwissProt: P70121 Mouse

SwissProt: Q8R515 Rat

Unigene: 612084 Human

Unigene: 244931 Mouse

Unigene: 16902 Rat



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