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NHP2L1 Rabbit pAb (bs-19236R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19236R
英文名稱 NHP2L1 Rabbit pAb
中文名稱 NHP2核糖核蛋白樣蛋白1抗體
別    名 [U4/U6.U5] tri snRNP; 15.5 kD RNA binding protein; High mobility group like nuclear protein 2 homolog 1; hSNU13; NHP2 non histone chromosome protein 2 like 1(S. cerevisiae); NHP2L 1; NHP2L1; NH2L1_HUMAN; NHPX; OTK27; SNU13.  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NHP2L1: 51-128/128 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri snRNP. It binds to the 5' stem loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.

Subunit:
Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, WDR57, SNRNP40, DDX23, CD2BP2, PPIH, NHP2L1, EFTUD2, SART1 and USP39. Interacts with RAD17 and PRPF31.

Subcellular Location:
Nucleus ?nucleolus. Note: Concentrated in the dense fibrillar component of the nucleolus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the ribosomal protein L7Ae family.

SWISS:
P55769

Gene ID:
4809

Database links:

Entrez Gene: 4809 Human

Entrez Gene: 321114 Zebrafish

Omim: 601304 Human

SwissProt: P55769 Human

Unigene: 182255 Human



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