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RBPMS Rabbit pAb (bs-19780R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-19780R
英文名稱 RBPMS Rabbit pAb
中文名稱 RBPMS蛋白抗體
別    名 FLJ32971; Heart and RRM expressed sequence; Hermes; RBP MS; RBP-MS; Rbpms; RBPMS_HUMAN; RNA binding protein gene with multiple splicing; RNA-binding protein with multiple splicing.  
研究領(lǐng)域 細胞生物  結(jié)合蛋白  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Dog,GuineaPig)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 22 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBPMS: 1-100/196 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Function:
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Ubiquitously expressed, at various levels depending on the isoform and the tissue.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q93062

Gene ID:
11030

Database links:

Entrez Gene: 428738 Chicken

Entrez Gene: 614417 Cow

Entrez Gene: 11030 Human

Entrez Gene: 19663 Mouse

Entrez Gene: 498642 Rat

Omim: 601558 Human

SwissProt: Q9W6I1 Chicken

SwissProt: Q93062 Human

SwissProt: Q9WVB0 Mouse

Unigene: 334587 Human

Unigene: 323997 Mouse



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