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SLC47A1 Rabbit pAb (bs-9284R)  
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產(chǎn)品編號 bs-9284R
英文名稱 SLC47A1 Rabbit pAb
中文名稱 溶質(zhì)載體蛋白家族47成員A1抗體
別    名 1A1; AIM 1; AIM1; MATP; Melanoma antigen AIM1; Membrane associated transporter; Membrane associated transporter protein; Membrane-associated transporter protein; Protein AIM 1; Protein AIM-1; Protein AIM1; S45A2_HUMAN; SHEP5; SLC45A2; Solute carrier family 45 member 2; Underwhite.  
Specific References  (1)     |     bs-9284R has been referenced in 1 publications.
[IF=6.208] Muhammad Erfan Uddin. et al. MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia. INT J MOL SCI. 2022 Jan;23(15):8607  IHC ;  Mouse.  
研究領域 腫瘤  細胞生物  信號轉導  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat (predicted: Rabbit,Sheep,Cow,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 58 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SLC47A1: 211-310/530 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]

Function:
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.

Subcellular Location:
Cell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.

Tissue Specificity:
Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).

Similarity:
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.

SWISS:
Q96FL8

Gene ID:
55244

Database links:

Entrez Gene: 55244 Human

Omim: 609832 Human

SwissProt: Q96FL8 Human

Unigene: 232054 Human



產(chǎn)品圖片
Sample: 293T Cell (Human) Lysate at 40 ug Adrenal gand (Mouse) Lysate at 40 ug Primary: Anti-SLC47A1 (bs-9284R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 62 kD
Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30mi
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