| 產(chǎn)品編號 | bs-7154R |
| 英文名稱 | ZNF139/ZKSCAN1 Rabbit pAb |
| 中文名稱 | 鋅指蛋白139抗體 |
| 別 名 | ZKSC1_HUMAN; Zinc finger protein with KRAB and SCAN domains 1; ZKSCAN1; Zinc finger protein 139; Zinc finger protein 36; Zinc finger protein KOX18; KOX18, ZNF139, ZNF36; PHZ-37; ZSCAN33; zinc finger with KRAB and SCAN domains 1; |
| 研究領(lǐng)域 | 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 64 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF139: 61-160/563 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010] Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 6 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 1 SCAN box domain. SWISS: P17029 Gene ID: 7586 Database links: Entrez Gene: 7586 Human Entrez Gene: 74570 Mouse SwissProt: P17029 Human SwissProt: Q8BGS3 Mouse Unigene: 615360 Human Unigene: 213114 Mouse Unigene: 113295 Rat |
| 產(chǎn)品圖片 |
Western blot analysis of lysates from MCF-7 cells, primary antibody was diluted at 1:1000, 4°over night
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