產(chǎn)品編號 | bsm-30041M |
英文名稱 | human CD45RA Mouse mAb |
中文名稱 | 小鼠抗人CD45RA單克隆抗體 |
別 名 | GP180; L-CA; LCA; LY5; T200; PTPRC; |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 45F1 |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | Flow-Cyt=1ug/Test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | kDa |
檢測分子量 | 205-220 |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CD45RA |
亞 型 | Mouse IgG1, k |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS (pH7.4). |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/na?ve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. SWISS: P08575 Gene ID: 5788 Database links: Entrez Gene: 5788 Human Omim: 151460 Human SwissProt: P08575 Human Unigene: 654514 Human |
產(chǎn)品圖片 | |