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PGK1 Rabbit pAb (bs-21867R)  
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產(chǎn)品編號(hào) bs-21867R
英文名稱(chēng) PGK1 Rabbit pAb
中文名稱(chēng) 磷酸激酶1抗體
別    名 Cell migration-inducing gene 10 protein; MGC117307; MGC8947; MIG10; pgk1; PGK1_HUMAN; PGKA; phosphoglycerate kinase 1; Primer recognition protein 2; PRP 2; PRP 2.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  激酶和磷酸酶  新陳代謝  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 44 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PGK1: 81-180/417 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19. [provided by RefSeq]

Function:
In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).

Subunit:
Monomer.

Subcellular Location:
Cytoplasm.

DISEASE:
Phosphoglycerate kinase 1 deficiency (PGK1D) [MIM:300653]: A condition with a highly variable clinical phenotype that includes hemolytic anemia, rhabdomyolysis, myopathy and neurologic involvement. Patients can express one or more of these manifestations. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the phosphoglycerate kinase family.

SWISS:
P00558

Gene ID:
5230

Database links:
Entrez Gene: 5230 Human

Entrez Gene: 18655 Mouse

Entrez Gene: 24644 Rat

Omim: 311800 Human

SwissProt: P00558 Human

SwissProt: P09411 Mouse

SwissProt: P16617 Rat

Unigene: 78771 Human

Unigene: 336204 Mouse

Unigene: 336205 Mouse

Unigene: 108127 Rat



產(chǎn)品圖片
Sample: Kidney (Mouse) Lysate at 40 ug Primary: Anti- PGK1 (bs-21867R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 44 kD Observed band size: 44 kD
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