| 產品編號 |
bsk11046 |
| 英文名稱 |
Human Pro-Collagen I alpha 1 ELISA Kit
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| 中文名稱 |
人I型膠原α1前體酶聯(lián)免疫試劑盒 |
| 別 名 |
Collagen type I; Alpha 1 type I collagen; COL1A1; Collagen I alpha 1 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN; Chondrocalcin; collagen alpha-1(I) chain preproprotein. |
| 克 隆 號 |
|
| 種 屬 |
Human |
| 線性范圍 |
31.25 - 2,000 pg/mL |
| 應用范圍 |
S/P/CC |
| 檢測限 |
7 pg/mL |
| 適用樣品基質 |
cell culture supernates, serum, and plasma. |
| 保存條件 |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.). |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008].
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