產(chǎn)品編號 | bs-48003P |
英文名稱 | Recombinant human IL-17A protein (Active, HEK293) |
中文名稱 | 重組人白細(xì)胞介素-17 (活性的) |
別 名 | rhIL-7; Interleukin-17; CTLA 8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; IL 17A; IL17A; IL-17A; Interleukin 17; Interleukin 17A; Interleukin17; Interleukin17A; Recombinant human IL-17A protein (Active, HEK293) IL-17 重組蛋白; 白細(xì)胞介素-17; 重組人白細(xì)胞介素-17; |
理論分子量 | 16kDa |
檢測分子量 | 2024-9-30 |
性 狀 | Liquid |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 20-155/155 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | <0.5 EU/μg as determined by LAL. |
表達(dá)系統(tǒng) | HEK293 cell |
活性 | Yes |
標(biāo)簽 | Tag free |
緩 沖 液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after r |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. IL-17(IL-17A) is a homodimer of two 136 amino acid chains that are secreted by activated T cells. IL-17A is expressed by activated Th17 cells. IL-17A induces stromal cells to produce proinflammatory and hematopoietic cytokines. It also enhances the surface expression of ICAM1 (intracellular adhesion molecule 1) in fibroblasts. This recombinant human IL-17(IL-17A) is produced by human cells. Biological activity: The activity was measured by its ability to stimulate the proliferation of murine 2E8 cells. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: Q16552 Gene ID: 3605 |
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