| 產(chǎn)品編號(hào) | bs-48009P |
| 英文名稱 | Recombinant human IL-29 protein (Active, HEK293) |
| 中文名稱 | 重組人白介素28B (活性的, Tag free) |
| 別 名 | Interleukin-29; rhIL-29; IL-29; IL 29; IL29; Interferon lambda-1; Cytokine ZCYTO21; IFN lambda 1; IFNL1; Interferon lambda 1; IFNL1_HUMAN. ;Recombinant human IL-29 protein (Active, HEK293) 人白介素29 重組蛋白; 人白細(xì)胞介素29 ; 重組人白介素29; 重組人IL-29; |
| 檢測分子量 | 29-35 |
| 性 狀 | Lyophilized |
| 濃 度 | ＞0.5 mg/ml |
| 物 種 | Human |
| 序 列 | 20-200/200 |
| 純 度 | >95% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | <0.5 EU/μg as determined by LAL. |
| 表達(dá)系統(tǒng) | HEK293 cell |
| 活性 | Yes |
| 標(biāo)簽 | Tag free |
| 緩 沖 液 | Lyophilized from 0.22um filtered solution in PBS (pH7.4) with 5mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
| 保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after r |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IL-29 belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL29 is induced by virus infection or double stranded RNA. IL-29 acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-29 has antiviral, antitumour and immunomodulatory activities. IL-29 is primarily active in epithelial cells and this cell type selective action is because of the epithelial cell specific expression of its receptor IFNLR1. It also exerts an immunomodulatory effect by up regulating MHC class I antigen expression. This recombinant human IL-29 is produced by human cells.(Tag free) Biological activity: The activity was measured by its antivirus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: Q8IU54 Gene ID: 282618 |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 95% as determined by reduced and non reduced SDS-PAGE
|
