| 產(chǎn)品編號(hào) | bs-1613R-BF750 |
| 英文名稱(chēng) | NeuN, BF750 conjugated |
| 中文名稱(chēng) | BF750標(biāo)記的神經(jīng)元核抗原抗體 |
| 別 名 | RFOX3_HUMAN; RNA binding protein fox-1 homolog 3; RBFOX3; Fox-1 homolog C; Neuronal nuclei antigen (NeuN antigen); FOX3; NEUN; FOX-3; HRNBP3; |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)運(yùn)蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 34kDa |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NeuN: 51-150/312 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2017] Function: RNA-binding protein that regulates alternative splicing events. Subcellular Location: Nucleus. Cytoplasm. Similarity: Contains 1 RRM (RNA recognition motif) domain. SWISS: A6NFN3 Gene ID: 146713 Database links: Entrez Gene: 146713 Human Entrez Gene: 52897 Mouse SwissProt: A6NFN3 Human SwissProt: Q8BIF2 Mouse Unigene: 135229 Human Unigene: 341103 Mouse Unigene: 143966 Rat |
