| 產(chǎn)品編號(hào) | bsm-30256A |
| 英文名稱 | mouse CD49d Rat mAb |
| 中文名稱 | 小鼠CD49d單克隆抗體 |
| 別 名 | alpha 4 subunit of VLA 4 receptor; ITG-α4: Antigen CD49D; CD 49d; Integrin alpha 4; CD49d antigen; CDw49d; IA4; Integrin alpha IV; ITGA 4; ITGA4; LPAM23; MGC90518; Very Late Activation Antigen 4; Very Late Activation Protein 4 Receptor alpha 4 Subunit; VLA 4; VLA4; integrin alpha-4; ITA4_HUMAN; Integrin α4; Integrin α 4. |
| 抗體來(lái)源 | Rat |
| 克隆類(lèi)型 | Monoclonal |
| 克 隆 號(hào) | 5A12 |
| 交叉反應(yīng) | (predicted: Mouse) |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-100
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 111 kDa |
| 檢測(cè)分子量 | 150 |
| 性 狀 | Liquid |
| 亞 型 | Rat IgG2b, k |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
