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Beta catenin, BF750 conjugated (bs-23663R-BF750)  
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100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23663R-BF750
英文名稱 Beta catenin, BF750 conjugated
中文名稱 BF750標(biāo)記的β-連環(huán)蛋白/β-連環(huán)素/β鏈接素抗體
別    名 beta-catenin; CHBCAT; CTNNB1; CTNNB; PRO2286; Cadherin associated protein; Catenin (cadherin associated protein), beta 1, 88kDa; Catenin beta 1; Catenin beta-1; CATNB; CTNB1_HUMAN; DKFZp686D02253; FLJ25606; FLJ37923; b-catenin; Catenin-β; Catenin β.  
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 86kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Beta catenin: 701-781/781 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

SWISS:
P35222

Gene ID:
1499

Database links:

Entrez Gene: 1499 Human

Entrez Gene: 12387 Mouse

Entrez Gene: 84353 Rat

Omim: 116806 Human

SwissProt: P35222 Human

SwissProt: Q02248 Mouse

SwissProt: Q9WU82 Rat

Unigene: 476018 Human

Unigene: 291928 Mouse

Unigene: 112601 Rat



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