| 產(chǎn)品編號(hào) | bsm-63159R |
| 英文名稱 | IL-1RA Recombinant Rabbit mAb |
| 中文名稱 | 白介素-1受體拮抗劑重組兔單抗 |
| 別 名 | DIRA; ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); Interleukin-1 receptor antagonist protein; IRAP; Type II interleukin 1 receptor antagonist. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 7B11 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:5000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200,IP=1:20-1:50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 20 kDa |
| 檢測(cè)分子量 | 20 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human IL 1RN: 120-177/177 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens. SWISS: P18510 Gene ID: 3557 ????L-lra-重組人白介素-1受體拮抗劑，通過與白細(xì)胞介素-1的Ⅰ型和Ⅱ型受體結(jié)合，特異性地阻斷白細(xì)胞介素-1的生物學(xué)作用。白介素1受體拮抗劑(IL-1Ra)是體內(nèi)天然的一種對(duì)IL-1有拮抗作用的細(xì)胞因子。國(guó)際上對(duì)其的研究愈來愈受到重視。 重組人白介素1受體拮抗劑(rhIL-1Ra)作為一種生物制劑已經(jīng)FDA批準(zhǔn)應(yīng)用于臨床治療細(xì)胞因子。 ????重組白介素1受體拮抗劑，分子量約17kD，純度大于98%。 |
