| 產(chǎn)品編號 | bsm-63162R |
| 英文名稱 | IRS1 Recombinant Rabbit mAb |
| 中文名稱 | 胰島素受體底物-1重組兔單抗 |
| 別 名 | HIRS1; Insulin receptor substrate 1; IRS 1; IRS1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 5B3 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 132 kDa |
| 檢測分子量 | 170 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human IRS 1: 1100-1200 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2. SWISS: P35568 Gene ID: 3667 信號傳導(dǎo)（Signaling Intermediates） 胰島素受體底物-1是細胞中分子量為165-185kDa的磷蛋白，胰島素受體的內(nèi)源性底物。經(jīng)胰島素刺激后其酪氨酸殘基被磷酸化。 |
