| 產(chǎn)品編號(hào) | bsm-63279R |
| 英文名稱 | phospho-EIF2AK2 (T451) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化干擾素誘導(dǎo)的雙鏈RNA活化蛋白激酶重組兔單抗 |
| 別 名 | EIF2AK1; EIF2AK2; p68 kinase; PKR; PPP1R83; PRKR; Protein kinase RNA activated. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 3G8 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 62 kDa |
| 檢測(cè)分子量 | 68 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human eIF2A K2 around the phosphorylation site of T451: SKG-pT-LRY |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to viral infection. SWISS: P19525 Gene ID: 5610 蛋白激酶R/雙鏈RNA依賴蛋白激酶（PKR）是一種干擾素誘導(dǎo)的、雙鏈RNA激活的絲氨酸/蘇氨酸激酶, PKR在信號(hào)轉(zhuǎn)導(dǎo)、細(xì)胞生長、分化和凋亡的控制中起重要作用.也有人認(rèn)為：PKR是一個(gè)重要的凋亡效應(yīng)物,是許多不同刺激物誘導(dǎo)凋亡的一個(gè)轉(zhuǎn)導(dǎo)物。 |
