| 產(chǎn)品編號(hào) | BIO0275SM |
| 英文名稱 | Anti-human TROP2 (Sacituzumab Biosimilar) |
| 中文名稱 | |
| 抗體來源 | |
| 克隆類型 | Monoclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 145.52 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Lyophilized |
| 亞 型 | Human IgG1 |
| 純化方法 | Protein A |
| 保存條件 | For long term storage, the produce should be stored at -20°C or lower. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
Human TROP2 HEK293 cells were stained with Anti-TROP2 Reference Antibody (sacituzumab) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.4071 ug/mL.
The endocytosis ratio sacituzumab by human TROP2 HEK293 increased with the increase of antibody concentration, and the Internalization Rate (%) reached 70% at antibody concentration of 0.4 nM.
Immobilized human TROP2 His at 2 ug/mL can bind Anti-TROP2 Reference Antibody (sacituzumab), EC50=0.004316 ug/mL.
The purity of Anti-TROP2 Reference Antibody (sacituzumab) is 96.23%, determined by SEC-HPLC.
Anti-TROP2 Reference Antibody (sacituzumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
|
