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Human CD40L Mouse mAb (V7904)  
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產(chǎn)品編號 V7904
英文名稱 Human CD40L Mouse mAb
中文名稱 CD40L(CD154)單克隆抗體
別    名 TNFSF5; CD 154; CD 40L; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor(ligand) superfamily member 5; CD40L_HUMAN.  
克 隆 號 5F6
理論分子量 29 kDa
檢測分子量
性    狀 Liquid
純    度 >90% as determined by SDS-PAGE
緩 沖 液 0.01M PBS(pH7.4)
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.

SWISS:
P29965

Gene ID:
959

V7904
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