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Rabbit Anti-TCERG1/APC Conjugated antibody (bs-6801R-APC)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6801R-APC
英文名稱 Rabbit Anti-TCERG1/APC Conjugated antibody
中文名稱 APC標(biāo)記的轉(zhuǎn)錄延伸調(diào)節(jié)蛋白1抗體
別    名 CA 150; Co activator of 150 kDa; Coactivator of 150 kDa; MGC133200; TAF 2S; TAF2S; TATA box binding protein (TBP) associated factor RNA polymerase II S 150kD; TATA box binding protein associated factor 2S; TATA box binding protein associated factor RNA polymerase II S 150kD; TCERG 1; TCERG1; Transcription elongation regulator 1; Transcription factor CA 150; Transcription factor CA150; TCRG1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 腫瘤  轉(zhuǎn)錄調(diào)節(jié)因子  腫瘤細(xì)胞生物標(biāo)志物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TCERG1/CA150
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CA150 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. It interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.

Function:
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.

Subunit:
Binds formin (By similarity). Binds RNA polymerase II, HD and SF1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Detected in brain neurons.

Similarity:
Contains 6 FF domains.

Database links:
UniProtKB/Swiss-Prot: O14776.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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