日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質(zhì)量反饋  關于我們  聯(lián)系我們
亚洲一区二区性爱,免费看黄色录像视频,96亚洲一二三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Ankyrin G/PE Conjugated antibody (bs-2415R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-2415R-PE
英文名稱 Rabbit Anti-Ankyrin G/PE Conjugated antibody
中文名稱 PE標記的錨定蛋白G抗體
別    名 ANK-3; ANK-3; ANK3; ANK3_HUMAN; ankyrin 3 (G); Ankyrin 3, node of Ranvier (ankyrin G); Ankyrin 3, node of Ranvier; Ankyrin G119; Ankyrin-3; Ankyrin-G; brain specific ankyrin G; CHANK3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經(jīng)生物學  信號轉導  細胞粘附分子  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 481/220kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Ankyrin G
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
human: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact, and the maintenance of specialized membrane domains. Multiple isoforms of ankyrin with different affinities for various target proteins are expressed in a tissue-specific, developmentally regulated manner. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Alternatively spliced variants may be expressed in other tissues. Although multiple transcript variants encoding several different isoforms have been found for this gene, the full-length nature of only two have been characterized. [provided by RefSeq]
mouse: This gene encodes a member of the ankyrin protein family. Ankyrins link integral membrane proteins to the spectrin-based Ankyrins link integral membrane proteins to the spectrin-based cytoskeleton. Ankyrin family members share a protein structure which includes three independently folded domains: the N-terminal ankyrin repeat domain, the central spectrin-binding domain, and the C-terminal rod domain. This ankyrin functions as the major ankyrin in the kidney and may play a role in the polarized distribution of many integral membrane proteins to specific subcellular sites. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Function:
In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments.

Subunit:
Directly interacts with DMD and betaDAG1. This interaction does not interfere with binding between DMD and betaDAG1. It is also required for DMD and betaDAG1 retention at costameres (By similarity). Interacts (via N-terminal ANK repeats) with SCHIP1 isoform 5 (via C-terminus); this interaction is required for the localization at axon initial segments (AISs) and nodes of Ranvier (NRs) (By similarity). May be a constituent of a neurofascin/NRCAM/ankyrin G complex. Interacts with RHBG.

Subcellular Location:
Cytoplasm, cytoskeleton. Cell junction, synapse, postsynaptic cell membrane (By similarity). Lysosome (By similarity). Note=In skeletal muscle, localized at costameres and neuromuscular junctions (By similarity). In macrophages, associated with lysosomes (By similarity).

Tissue Specificity:
Expressed in brain, neurons and other tissues.

DISEASE:
Note=Genetic variations in ANK3 are associated with autism spectrum disorders susceptibility.

Similarity:
Contains 23 ANK repeats.
Contains 1 death domain.
Contains 2 ZU5 domains.

Database links:

Entrez Gene: 288 Human

Entrez Gene: 11735 Mouse

Entrez Gene: 361833 Rat

Omim: 600465 Human

SwissProt: Q12955 Human

SwissProt: G5E8K5 Mouse

SwissProt: Q4U206 Mouse

Unigene: 499725 Human

Unigene: 235960 Mouse

Unigene: 202383 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

錨定蛋白G是一個分子量在480KDa大分子細胞內(nèi)蛋白。 錨蛋白(ankyrin)錨蛋白屬于聯(lián)結蛋白家族,廣泛存在于各種組織細胞中。錨蛋白連接整合膜蛋白到細胞骨架蛋白網(wǎng)絡,在多種細胞功能活動中起關鍵作用,參與機體生長、發(fā)育、細胞內(nèi)蛋白轉運、細胞極性的建立和維持、細胞黏附、信號傳導以及mRNA轉錄等。
版權所有 2004-2026 m.bklrv.cn 北京博奧森生物技術有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
丁香五月婷婷在线观看无| 国产系列久久| 少妇人妻电影| 欧美日韩国产 一页| 亚洲日韩欧美国产精品一区二区| 精品人妻一区二区三区四季av| 九九熟妇五月天| A片免费久久久青青草| 亚洲激情 在线| 98人人操人人摸夜夜嗨| 太久免费在线观看| 热九九小黄片| 大美女操逼视频播放| 激情成人国产午夜| 色中色色91| 91在线中文字幕2| 日本一视频二视频| 痲妃一区二区三区| 五月激激综合| 宅男久久国产精品| 亚洲AV永久无码精品久久麻豆| 少妇3P久久aV激情| 好吊视频免费在线观看| 最新高清日韩无码| 亚洲福利视频久久| 天天爱天天射天天舔| 黄色网址av| 日韩专区一区二区三区高清| 国产成年无码久久久毛片| 啪啪啪欧美视频免费在线观看| 日韩亚洲欧美中文高清| 亚洲乱淫| 久久大香蕉性交| 黄片特一级| 日本三级韩国三级亚洲一区二区三区| 色婷婷久久综合中文久久一本| 极品少妇一区二区视频| 中文字幕在线视频播放| 一级片人妻欧美| 干干射射射亚州AV| 久久国产欧美在线|