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Rabbit Anti-MREG/Gold Conjugated antibody (bs-9665R-Gold)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9665R-Gold
英文名稱 Rabbit Anti-MREG/Gold Conjugated antibody
中文名稱 膠體金標記的MREG蛋白抗體
別    名 Dilute suppressor; Dilute suppressor protein homolog; DSU; Melanoregulin; MGC90296; MREG; WDT 2; WDT2; Whn dependent transcript 2; MREG_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 心血管  細胞生物  免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DSU/MREG
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

Function:
Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells.

Subunit:
Interacts with PRPH2.

Subcellular Location:
Apical cell membrane; Peripheral membrane protein.

Tissue Specificity:
Expressed in photoreceptor cells (at protein level).

Similarity:
Belongs to the melanoregulin family.

Database links:

Entrez Gene: 55686 Human

Entrez Gene: 381269 Mouse

Omim: 609207 Human

SwissProt: Q8N565 Human

SwissProt: Q6NVG5 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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