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Rabbit Anti-NMS/Gold Conjugated antibody (bs-11443R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11443R-Gold
英文名稱 Rabbit Anti-NMS/Gold Conjugated antibody
中文名稱 膠體金標記的神經(jīng)調(diào)節(jié)肽S抗體
別    名 Neuromedin S; Neuromedin-S; NeuromedinS; Nms; NMS_HUMAN; Prepro NMS.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學  信號轉(zhuǎn)導  生長因子和激素  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 4kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuromedin S
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
NMS is a 153 amino acid secreted protein that belongs to the NmU family. NMS is implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions. The gene that encodes NMS consists of approximately 12,799 bases and maps to human chromosome 2q11.2. Consisting of 237 million bases and encoding over 1,400 genes, chromosome 2 makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8.

Function:
NMS (neuromedin S) is a 36-amino acid neuropeptide specifically expressed in the suprachiasmatic nucleus (SCN) of the hypothalamus. NMS shares a C-terminal core structure with NMU. NMS mRNA is highly expressed in the central nervous system, spleen and testis. NMS may be implicated in the regulation of circadian rhythms and feeding behavior.

Subcellular Location:
Secreted.

Similarity:
Belongs to the NmU family.

Database links:

Entrez Gene: 129521 Human

SwissProt: Q5H8A3 Human

Unigene: 567676 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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