日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国内女主播操逼电影,国产六九精品,国产激情亚洲综合五月天
Rabbit Anti-phospho-AANAT (Thr29)/BF647 Conjugated antibody (bs-11448R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11448R-BF647
英文名稱 Rabbit Anti-phospho-AANAT (Thr29)/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的磷酸化芳香胺N-乙?;D(zhuǎn)移酶抗體
別    名 p-AANAT(Thr29); p-AANAT(T29); AANAT(phospho Thr29); p-AANAT(phospho-T29); Serotonin N-acetyltransferase (phospho T29); AANAT (phospho-Thr29); AANAT; Arylalkylamine N acetyltransferase; SNAT_HUMAN; Serotonin N-acetyltransferase; SNAT; Serotonin acetylase; Aralkylamine N-acetyltransferase; AA-NAT.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human AANAT around the phosphorylation site of Thr29
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Arylalkylamine N-acetyltransferase belongs to the superfamily of acetyltransferases. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for seasonal reproduction, modulates the function of the circadian clock in the suprachiasmatic nucleus, and influences activity and sleep. This enzyme is rapidly inactivated when animals are exposed to light at night. This protein is 80% identical to sheep and rat AA-NAT. Arylalkylamine N-acetyltransferase may contribute a multifactorial genetic diseases such as altered behavior in sleep/wake cycle.

Function:
Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.

Subunit:
Monomer. Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with lower affinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation. It may also prevent thiol-dependent inactivation.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland.

Post-translational modifications:
cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins.

DISEASE:
Delayed sleep phase syndrome (DSPS) [MIM:614163]: A circadian rhythm sleep disorder characterized by sleep-onset insomnia and difficulty in awakening at the desired time. Patients with DSPS have chronic difficulty in adjusting their sleep-onset and wake-up times to occupational, school, and social activities. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry. Susceptibility to delayed sleep phase syndrome can be conferred by variant Thr-129. Thr-129 shows a significantly higher frequency in affected individuals than in healthy controls.

Similarity:
Belongs to the acetyltransferase family. AANAT subfamily.
Contains 1 N-acetyltransferase domain.

Database links:

Entrez Gene: 503504 Chimpanzee

Entrez Gene: 15 Human

Entrez Gene: 11298 Mouse

Entrez Gene: 25120 Rat

SwissProt: P79774 Chicken

SwissProt: Q5IS55 Chimpanzee

SwissProt: Q16613 Human

SwissProt: O88816 Mouse

SwissProt: Q64666 Rat

Unigene: 431417 Human

Unigene: 418559 Mouse

Unigene: 42233 Mouse

Unigene: 88180 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
日韩第四页| 日本一区韩国二区欧美三区| 久久久久久色| 自拍偷拍大图国产| 亚洲自拍激情| 色呦呦一品| 日美、骚逼视频| 不卡的av手机观看_| 国产二区超碰在线| www.人妻偷拍| 黄色片网站久久久久www| 精品无人乱码一区二区三 | 午夜精品电信在线观看| 要干就干去干激情五月天| 熟女三二区| 日韩无码啊嗯| 操河南熟女视频| ↗日韩欧美一区二| 精品日韩免费观| 少妇高潮 30p| 日本欧美在线视频| 中文字幕919399人妻一区| 欧美168黄片| 中文字幕无码欧美日产| 亚洲精品无语久久妻| 尤物无码白丝一区二区| A黄片久一点| 中美一级片色网站| 在线人妻巨乳第一页| 久久无码99| 大鸡扒艹骚逼| 岛国中文字幕av伊人| 三级片青青草原| 国产亚洲成人综合在线| 色天天色综合| 视频一区二区二区| av影音资源| 国产欧美日韩国生产一区二区| 超碰久色伊人| 亚洲无码汽车| 欧洲人妖一区二区三区在线观看|