產(chǎn)品編號(hào) | bs-11471R-Gold |
英文名稱1 | Rabbit Anti-PTPRD/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的酪氨酸磷酸酶PTPδ抗體 蛋白酪氨酸磷酸酶D受體抗體 |
別 名 | protein tyrosine phosphatase receptor type D; RPTP Delta; Tyrosine phosphatase Delta; PTPRD_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 212kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PTPRD (783-830aa) |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: RelevancePTPRD is a protein tyrosine phosphatase that falls into the receptor-type group as it characteristically comprises an extracellular region, a single transmembrane region and two tandem cytoplasmic catalytic domains. The extracellular region of this protein contains 3 Ig-like and 8 fibronectin type III-like domains. This protein is thought to be involved in promoting neurite growth and in axonal guidance. Subunit: Interacts with IL1RAPL1 (via extracellular region); interaction is required for IL1RAPL1-mediated synapse formation (By similarity). Interacts with PPFIA1, PPFIA2 and PPFIA3. Subcellular Location: Membrane; Single-pass type I membrane protein. Post-translational modifications: A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily. Contains 8 fibronectin type-III domains. Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 2 tyrosine-protein phosphatase domains. Database links: Entrez Gene: 5789 Human Omim: 601598 Human SwissProt: P23468 Human Unigene: 446083 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |