日日操日日操,亚洲日本午夜激情,人妻内射精品一区二区,国产一区北条麻妃

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品头伦一区二,一区二区三区亚洲欧美日韩
Rabbit Anti-DVL1/PE-Cy5.5 Conjugated antibody (bs-0598R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0598R-PE-Cy5.5
英文名稱 Rabbit Anti-DVL1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的蓬亂蛋白1抗體
別    名 Dishevelled 1; Dishevelled; Dishevelled dsh homolog 1; Dishevelled1; DSH homolog 1; Dvl; MGC54245; Segment polarity protein dishevelled homolog DVL 1; Segment polarity protein dishevelled homolog DVL1; DVL1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 76kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DVL1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
DVL1 may play a role in the signal transduction pathway mediated by multiple Wnt genes. [Subunit] Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts (via PDZ domain) with NXN (By similarity). Interacts with CXXC4. [Subcellular Location] Cytoplasm (Potential). Belongs to the DSH family.

Function:
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

Subunit:
Interacts with CXXC4. Interacts (via PDZ domain) with NXN (By similarity). Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts with ARRB1; the interaction is enhanced by phosphorylation of DVL1. Interacts with CYLD (By similarity). Interacts (via PDZ domain) with RYK. Self-associates (via DIX domain) and forms higher homooligomers. Interacts (via PDZ domain) with DACT1 and FZD7, where DACT1 and FZD7 compete for the same binding site (By similarity). Interacts (via DEP domain) with MUSK; the interaction is direct and mediates the formation a DVL1, MUSK and PAK1 ternary complex involved in AChR clustering (By similarity).

Subcellular Location:
Cell membrane. Cytoplasm, cytosol. Cytoplasmic vesicle. Localizes at the cell membrane upon interaction with frizzled family members.

Post-translational modifications:
Ubiquitinated; undergoes both 'Lys-48'-linked ubiquitination, leading to its subsequent degradation by the ubiquitin-proteasome pathway, and 'Lys-63'-linked ubiquitination. The interaction with INVS is required for ubiquitination. Deubiquitinated by CYLD, which acts on 'Lys-63'-linked ubiquitin chains.

Similarity:
Belongs to the DSH family.
Contains 1 DEP domain.
Contains 1 DIX domain.
Contains 1 PDZ (DHR) domain.

Database links:

Entrez Gene: 1855 Human

Entrez Gene: 13542 Mouse

Entrez Gene: 83721 Rat

Omim: 601365 Human

SwissProt: Q5IS48 Chimpanzee

SwissProt: O14640 Human

SwissProt: P51141 Mouse

SwissProt: Q9WVB9 Rat

Unigene: 741165 Human

Unigene: 3400 Mouse

Unigene: 144610 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

dishevelled-1蓬亂蛋白-1主要用于神經(jīng)退行性改變-AD病方面的研究.
版權(quán)所有 2004-2026 m.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
无码B片| 色色色综合国产精品| 综合一和综合二的无码| 精品少妇极品久久久| 字幕网中文在线资源站丝袜| 日韩少妇高清av在线| 日本不卡高清久久| 人妻在线日韩免费视频| 天天躁日日躁AAAXXⅩ| 亚洲性色图片| 亚洲黄色国产三级| 香蕉视频黄色片A级黄色片| 精品一区二区蜜臀视屏| 麻豆传媒 在线资源| 日本免费一级二级免费| 日韩熟妇无码中文字幕| 丁香五五婷婷网| 范冰冰和佟大为真干嘛| 亚洲一级Av无码毛片久欠精品| 亚洲成人三级视频| 欧美激情婷婷五月| 南溪县| 亚洲精品二区五码| 日韩欧美人妻之中文字墓| 欧美日韩国产首页一区| 欧美中文无码品二区| 透欧美美女的逼| 谷原希美的AV在线| 婷婷激情五月 欧美综合| 7久视频| 少妇AV综合小说| 乱色老熟女| 日韩欧美性| 被大鸡八操骚逼高潮喷水| 看操小穴视频| 乱色老一区二区三区| 日本一道一区二区视频什么时候播出| 调教嫩草专区| 麻豆中文在线观看| 亚洲天堂A亚洲| 综合区小说区AV|