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Rabbit Anti-R-cadherin/Biotin Conjugated antibody (bs-3675R-Bio)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-3675R-Bio
英文名稱(chēng) Rabbit Anti-R-cadherin/Biotin Conjugated antibody
中文名稱(chēng) 生物素標(biāo)記的R-鈣粘附分子抗體
別    名 Cadherin 4; Cadherin4; Cadherin-4 CDH4; R CAD; Retinal Cadherin.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  激酶和磷酸酶  細(xì)胞粘附分子  糖蛋白  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 81kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human R-cadherin(423-475aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cadherins constitute a superfamily of calcium-dependent intercellular adhesion molecules and are thought to play a role in cell recognition and segregation, morphogenetic regulation, and tumor suppression. R Cadherin is expressed mainly in the brain but is also found in other tissues.

Function:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Tissue Specificity:
Expressed mainly in brain but also found in other tissues.

Similarity:
Contains 5 cadherin domains.

Database links:

Entrez Gene: 1002 Human

Entrez Gene: 12561 Mouse

Entrez Gene: 114588 Rat

Omim: 603006 Human

SwissProt: P55283 Human

SwissProt: P39038 Mouse

SwissProt: Q80ZV4 Mouse

SwissProt: Q63149 Rat

Unigene: 473231 Human

Unigene: 598638 Human

Unigene: 184711 Mouse

Unigene: 382094 Mouse

Unigene: 392073 Mouse

Unigene: 214089 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

R-鈣粘附分子,是依賴(lài)鈣離子的細(xì)胞間糖蛋白粘附分子的一種,主要是參與細(xì)胞間同源性粘附、調(diào)控和介導(dǎo)細(xì)胞間相互反應(yīng),在腫瘤的遷移、分化中起到一定的作用。在腦組織中表達(dá)外,其他組織中已有定位。
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